Pulmonary function tests and micro-CT analysis demonstrated that Prdx3 silencing increased pulmonary fibrosis in BLM-treated YAP1-cKI mice, indicating that YAP1 inhibited BLM-induced pulmonary fibrosis through Prdx3 in vivo (Fig. 8b, c). This evidence concerns the gene YAP1 and pulmonary fibrosis.