Considering the differential localization, abundance, and metabolic activity of the different forms of nitrated Hsp90, an interesting hypothesis to explore in the future, proposing a dual role for the nitrated chaperone in tumor growth, is that in the highly proliferative cell layer with access to oxygen and nutrients, Hsp90NY33 decreases oxygen consumption while Hsp90NY56 increases glycolysis to produce metabolic intermediates that support active cell proliferation. Here, HSP90AB1 is linked to neoplasm.