Our objective, therefore, was to evaluate the longitudinal association of circulating levels of n-3 PUFAs with sCD163 and adiponectin, which are established biomarkers of AT inflammation and function, using data from a well-characterized longitudinal observational cohort of adults at high risk for type 2 diabetes (T2D) (24, 25). The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.