In addition to genes discussed previously (ANK2, WFS1, TNC, TRIOBP, and OTOGL), this group includes LRBA, a gene required for maintenance of cochlear hair cells [33], and MPDZ, a gene implicated in autosomal recessive nonsyndromic hearing impairment [34] This group of genes, with more conservative selection criteria, may form the basis of a new screening panel for MD. Here, WFS1 is linked to Menkes disease.