KDM7A and head and neck squamous cell carcinoma: Furthermore, analyses of HNSCC patient data showed that miR-451a and KDM7A are significant risk factors for cetuximab resistance in HNSCC, suggesting the great potential of miR-451a and KDM7A to serve as cetuximab resistance biomarkers or potential targets for overcoming cetuximab resistance in HNSCC.