Increased TRX-1 levels have been shown as a potential tool for predicting favorable prognosis in patients with acute ischemic stroke.22 In patients with coronary artery disease, decreased serum TRX-1 levels were closely correlated with the extent and severity of coronary artery disease.23 In this context, an attempt was made by Haga et al. to identify TRX-1 as a biomarker for BPD. The gene discussed is TXN; the disease is coronary artery disorder.