Of the druggable targets 31 (ADRB1, ENPEP, EPHA3, FGFR1, HBEGF, HCN4, IL6R, KCNH2, KCNJ5, MAPT, MC4R, MET, MYH6, MYL4, NDUFAF3, NDUFB10, NPR3, PDE3A, PDE4B, PRKCA, PSMB7, PTK2, SCN5A, SRD5A3, THRB, TNSFSF12, TNFSF13, TNNT3, TUBB3, WT1 and XPO1) were also associated with blood pressure and hypertension traits (Supplementary Table S11). This evidence concerns the gene SCN5A and hypertensive disorder.