– uPAR levels were higher in patients with SAP as compared to MSAP and MAP (P > .05)– Serum suPAR concentration was a significant indicator of organ failure, acute kidney injury, acute cardiovascular failure, and ICU transfer (P < .05)– suPAR levels were a significant predictor of in-hospital death (P < .05)– uPAR concentrations were linked with procalcitonin, IL-6, and CRP. Albumin and hematocrit were adversely linked with serum uPAR. The gene discussed is PLAUR; the disease is acute kidney injury.