In the previous nomenclature of metabolic associated fatty liver disease, formerly known as NFLD, it is characterized as a hepatic manifestation of metabolic syndrome with specific liver–pancreatic insulin resistance.[10] Thyroid hormones play a pivotal role in the regulation of insulin signaling and glucose homeostasis, which are crucial for metabolic equilibrium.[11] Previous research has established the critical role of thyroid hormones in modulating lipid and carbohydrate metabolism, energy homeostasis, and neurodevelopment. This evidence concerns the gene INS and fatty liver disease.