TNF and amebiasis: In terms of the intersecting targets from the KEGG pathway enrichment analysis, the top-ranked pathways included the tumor necrosis factor (TNF) signaling pathway, IL-17 signaling pathway, advanced glycation end products-receptor for advanced glycation end products signaling pathway in diabetic complications, fluid shear stress and atherosclerosis, lipids and atherosclerosis, rheumatoid arthritis, malaria, Toll-like receptor signaling pathway, African trypanosomiasis, amebiasis, and other pathways.