Among the 3415 upregulated genes, TMEM52B, previously identified in our report as a tumor suppressor in RCC,[12] showed a significant increase of more than 20‐fold (24.66) in all eight NPC cell lines compared to normal NPEC cells (Figure1A) (Data S1, Supporting Information), real‐time PCR (Figure 1B) and western blotting (Figure 1C) confirmed this observation. The gene discussed is TMEM52B; the disease is neoplasm.