A similar analysis performed on T cells following ex vivo reactivation with P/I revealed that the frequency of cytokine (IFN-γ, TNF-α, IL-2) producing memory (CD45RAneg) effector (TEM) and central memory (TCM) CD4+ or CD8+ T cells was highly heterogeneous in MM patients compared to HD (Supplementary Figure S2b, Figure 3(b)). The gene discussed is IFNG; the disease is Miyoshi myopathy.