Early detection of the urine albumin-creatinine ratio and extracoronary atherosclerosis may help guide the utility and timing of repeat CAC scoring in older persons with baseline CAC = 0.PERSPECTIVESCOMPETENCY IN MEDICAL KNOWLEDGE: Nearly one-half of persons ≥65 years of age developed incident CAC over a median-follow up time of <4 years. This evidence concerns the gene ALB and atherosclerosis.