The literature of the last 2 years shed light on lung and gastro-intestinal tract carcinomas as tumors with the highest correlation with Eg5 expression, followed by reproductive system carcinomas (breast, ovarian, and prostate) and central nervous system tumors; in other tumors (such as bladder cancer, renal cancer, and thyroid cancer) Eg5 overexpression is known, but less papers are available. The gene discussed is KIF11; the disease is central nervous system cancer.