KIF11 and lymphedema: However, the importance of KIF11 activity in the development and maintenance of retinal and lymphatic structures was highlighted by the fact that mutations in this gene were also detected in patients with chorioretinopathy and/or lymphedema, in addition to the microcephaly condition, supported by the finding that KIF11 is also localized in the inner segment and ciliary compartments of murine retina photoreceptor cells [110].