A previous study demonstrated that endogenous administration of KIF11 promoted the self-renewal of BC cells through BC stem cells and that after silencing of KIF11 a decrease in CSC markers is highlighted, ALDH1 included [84]; as a consequence, it is possible to state that a positive correlation between KIF11 expression and cancer stem markers exists, thus representing a possible therapeutic target. The gene discussed is ALDH1A1; the disease is breast cancer.