GOLM1 and hepatocellular carcinoma: Contributions of histone lactylation on HCC development have been recognized [55], although in the present study we demonstrated that histone lactylation could stimulate GP73 overexpression, and identified H3K4, H3K18, H4K5, and H4K as the lactylation sites on core histones [53], in particular, increased histone lactylation in H3K18 is required for the up-regulation of GP73.