IHC examinations showed decreased Ki-67 and pSTAT3-Ser727 levels in resected tumors originating from MHCC97H-c-Myc-OE- GP73-KD cells compared to MHCC97H-c-Myc-OE cells (Fig. 7J), while immunofluorescence analysis showed lower MVD and decreased CD34 and CD31 expressions in knocked down GP73 tumor-bearing tissues (Fig. 7K and Fig. S7G). The gene discussed is MKI67; the disease is neoplasm.