Specific genes increased in patients withoutlinezolid-associated neuropathy included ATG4C, BAX, and IGF1, while patients onlinezolid who suffered from neuropathy had an increase in AURKB, CASP3, CASP8, CDK1,CDKN1B, CEBPB, NADSYN1, NRF1, GPX7, and SBSN (Figure4B, Figure 4C, Supplementary Table2). This evidence concerns the gene NRF1 and neuropathy.