Gastrointestinal stromal tumour (GIST) cells and neoplastic MCs expressing constitutively active KIT variants release abundant populations of EVs and disseminate KIT in both microvesicle‐ and exosome‐like EVs of distinct composition (Atay et al., 2018; Kim et al., 2018; Pfeiffer et al., 2022; Xiao et al., 2014), suggesting a potential role for active KIT in the regulation of EV secretion. The gene discussed is KIT; the disease is gastrointestinal stromal tumor.