ZEB1 and colorectal carcinoma: Strikingly, spontaneous metastasis to the liver was decreased in FibΔZeb1 mice, regardless of AKP or AKPre transplantation, as reflected in the fraction of metastasis-bearing mice and the number of metastases per mouse (Fig. 1K,L), indicating a pro-metastatic role of ZEB1 in CAFs of sporadic and progressed CRC.