In this regard, it is important to mention that ZEB1 has been shown as a direct transcriptional (co-)inducer of inflammatory gene expression, like IL6, IL8 and others in several cell types, such as breast cancer cells and fibroblasts (Fu et al, 2019; Katsura et al, 2017), corneal fibroblasts, hematopoietic and myeloid cells (Cortes et al, 2017; Liang et al, 2022; Qian et al, 2021; Scott and Omilusik, 2019; Wang et al, 2009). This evidence concerns the gene IL6 and breast cancer.