Regulatory KIR+ CD8+ T cells in patients with autoimmune disease and SARS-CoV-2 infection shared a strong NK cell signature with our CD57+ Tex population13, as did Killer Cell Lectin-like Receptor (KLR)-expressing Tex cells (TexKLR) in mouse LCMV infection9,25. The gene discussed is KLRK1; the disease is autoimmune disease.