Taken all together, the current study shows that by the following combinations of protein markers is predictive of poor prognosis in CRC patients, 1) low stromal Fascin/high both cytoplasmic Fascin and stromal PN (low Fs/high FcPs) and 2) high cytoplasmic Fascin/nucelar Snail/stromal PN (high FcSnPs). This evidence concerns the gene FSCN1 and colorectal carcinoma.