In Regnase-1-deficient ILC2s and TH2cells there is an enrichment in Gata3 transcripts, which in T cellsis due to the RNase domain of Regnase-1 (45).This correlated with increases in type-2 responses (46), and in the ILC2 study, pulmonary fibrosis (59). This evidence concerns the gene GATA3 and pulmonary fibrosis.