Even though they are the same breast cancer subtype, they might be immuno-subtyped as neutrophil-enriched (NES, CD11b+ Ly6C mid Ly6G+) or macrophage-enriched (MES, CD11b+ Ly6G− Ly6C− F4/80+) based on their predisposition for recruiting TANs and TAMs which shown as mutually exclusive. This evidence concerns the gene ITGAM and breast cancer.