Proportion of TPN with NPE at 20-35 kcal/kg/day: 60.6% vs 70.7%; P = 0.004Ratio of energy from fat to energy from carbohydrates, up to 50%: 96.4% vs 100%; P > 0.05)Proportion of patients with serum albumin decrease: 76.7% vs 25.2% (P < 0.05); mean (SD) decrease, −8.11 (0.43) g/L vs −3.08 (0.44) g/L (P < 0.0001)Postoperative infection rate: 18.2% vs 11.6%Mean (SD) infection time: 9.4 (1.4) days vs 7.7 (1.0) days; P = 0.368Incidence of TPN-related hypoglycemia: 15.3% vs 5.4% The gene discussed is ALB; the disease is infection.