Moreover, the GFANIT mice showed elevated hepatic bile acids (Fig. 5L), ALT (Fig. 5M), AST (Fig. 5N), and concentrations of inflammatory cytokines (Fig. 5O through Q), and all of which indicated the inflamed and damaged liver as the results of the transplantation of gut microbiota from the donor mice with cholestasis. The gene discussed is GPT; the disease is cholestasis.