Inflammatory diseases, including neurodegenerative diseases, autoimmunediseases, cardiovascular disease, and cancer, among others, are characterizedby chronic inflammation which promotes disease progression.1,2 Inflammatory cytokines are key initiators and drivers of these diseases.Cytokines such as interleukin-6 (IL-6), interleukin-1 beta (IL-1β),interleukin-8 (IL-8), and tumor necrosis factor-α (TNF-α)are known therapeutic targets and biomarkers for these inflammatorydiseases.3−5 Platforms for cytokine detection are therefore desirabletools for both research and clinical applications. The gene discussed is TNF; the disease is neurodegenerative disease.