MAPT and early-onset autosomal dominant Alzheimer disease: Previous studies have demonstrated that the performance of cognitively complex everyday activities is associated with underlying Alzheimer's disease processes, i.e., accumulation of cerebral amyloid and tau (Okonkwo et al., 2010; Marshall et al., 2011, 2019b; Halawa et al., 2019; Dubbelman et al., 2023).