CBS and preeclampsia: Further on, an important characteristic of H2S-producing enzymes, CBS and CSE, is their ability to regulate homocysteine levels in the vicinity of cells through the production of H2S. This mechanism within the female reproductive tract serves to prevent pathological conditions such as hyperhomocysteinemia, which can lead to preeclampsia, miscarriages, congenital fetal abnormalities, and others.