Null-IFN-γ, Null-IL-8, CD3-IL-6, CD3-IL-8, CD3-IL-13, and ZYM IL-1β discriminated TB from TBI with a sensitivity of 73.9% (56.5%–91.3%) and a specificity of 100% (69.2%–100%). This evidence concerns the gene IL6 and tuberculosis.