RIPK3 and Salmonella Infections: Non-invasive S. typhimurium does not naturally induce RIPK3-dependent macrophage death, whereas macrophage necroptosis can only be induced when caspase is inhibited using Z-VAD-FMK, and RIPK3 induction (after caspase inhibition) does not affect host survival after systemic Salmonella infection (101).