For example, induction of mitophagy by the small molecule compounds kinetin, DFP, Urolithin A, UMI-77 and an inhibitor of USP30 at multiple steps in the mitophagy pathway has been considered a potential treatment for neurodegenerative diseases, including PD and Alzheimer's disease (AD) [36], [37], [38], [39], [40], [41]. The gene discussed is USP30; the disease is early-onset autosomal dominant Alzheimer disease.