We observed that carriers of the DRB1*09 allele in the primary phase of EBV infection had both higher log10 HIV viral loads (DRB1*09 = median: 5.67; IIQ: 5.56–5.76); (others = median: 4.45; IIQ: 3.85–5.33); p: 0.0176) (Figure 7A) and CD8(+) T lymphocyte counts (DRB1*09 = median: 2766.5; IIQ: 2506.5–2949.0); (others = median: 1024.5; IIQ: 834.5–2136.8); p: 0.0285) (Figure 7C) than carriers of other alleles. This evidence concerns the gene HLA-DRB1 and Epstein-Barr virus infection.