NFKB1 and acute respiratory distress syndrome: In animal experiments, overexpression of miR-146 reduced the secretion of pro-inflammatory cytokines by inhibiting the TNF receptor-associated factor 6 (TRAF6)/NFκB signaling pathway, inhibited the apoptotic response in the intestine and lung tissues of mice with II/R-ALI, and protected mice from II/R-ALI (47).