Xirp2 has been identified through single cell sequencing to be upregulated in sub-clusters of cardiomyocytes from human hypertrophic cardiomyopathy cardiac samples [54] and mutations within Xirp2 are linked to dilated cardiomyopathy [55] highlighting a further potential cardioprotective mechanism of 29P. This evidence concerns the gene XIRP2 and hypertrophic cardiomyopathy.