EGCG induced significant decreases in IL-1b and IFN-γ-induced nitric oxide production, and decreased levels of the inducible form of NO synthase (iNOS) mRNA and protein on RINm5F cells, suggesting that EGCG intake may help alleviate the symptoms of type 2 diabetes [41].Low-fat milk and whole milk do not show a harmful association with cardiovascular disease or type 2 diabetes in most observational and experimental evidence. Here, IL1B is linked to cardiovascular disorder.