Clinically, a robust correlation between RFX6 and AR expression was evident across multiple independent PCa cohorts[46, 47, 48, 49, 50, 51, 52] (Figure 1e and Extended Data Figure S1, Supporting Information), corroborating the notion of androgen signaling induced RFX6 upregulation in clinical contexts. The gene discussed is AR; the disease is posterior cortical atrophy.