HOXA10 and posterior cortical atrophy: Our study analyzed HOXA10 expression in various PCa patient cohorts[48, 49, 54, 60, 61] and found a significant correlation between its upregulation and advanced stages of PCa, particularly metastasis, and elevated levels of prostate‐specific antigen (PSA) (Figure 5a,b and Extended Data Figure S3c–j, Supporting Information), the latter is a golden‐standard biomarker for PCa screening and clinical decision‐making.[66] Furthermore, in mouse models with PTEN prostate‐specific knockout, HOXA10 expression was notably higher compared to wild‐type controls (Figure 5c,d).