One of them is VPM1002, a recombinant BCG vaccine that replaces the urease C gene in BCG with the gene-encoding Listeria monocytogenes hemolysin (Hly), which can induce a strong Th1 response [6] or produce completely new vaccines, such as the rhesus cytomegalovirus tuberculosis vaccine (RhCMV/TB), including vectors expressing nine different Mycobacterium tuberculosis (M. tb) proteins that activate and maintain a high-frequency T cell response and protect against Mycobacterium tuberculosis [7]. This evidence concerns the gene KRCC1 and tuberculosis.