It was also found that the expression level of CtBP2 in prostate cancer tissues was higher than in normal tissues, which was closely associated with the malignant behavior of the tumor, indicated by elevated serum prostatic specific antigen (PSA) levels, advanced tumor stage (T3), high Gleason score, and positive extraprostatic extension [67]. The gene discussed is CTBP2; the disease is prostate carcinoma.