BCL2L1 and infection: Chinese giant salamander (Andrias davidianus) iridovirus (GSIV) has been shown to regulate apoptosis in vitro, with GSIV promoting both intrinsic and extrinsic pathways of apoptosis in infected cells [67], with further in vitro studies by Li et al. (2021) showing that the Chinese giant salamander Bcl-xL was capable of limiting GSIV infection when overexpressed in cultured giant salamander muscle cells [68].