Furthermore, in PASC, reactivation of latent viruses like Epstein–Barr virus or cytomegalovirus may contribute to the pathogenesis due to either direct invasion and/or immune mediation (T cells and cytokines), particularly when autoantibodies targeting IFNα2 may impede the body’s immune response and correlate with increased levels of inflammatory cytokines [27,28,29,30]. This evidence concerns the gene IFNA2 and long COVID-19.