CAMK2N2 and myeloproliferative disorder: In addition, three other upregulated genes were found: the MPL gene encoding the thrombopoietin receptor associated with myeloproliferative disorder, the LIF gene, which is an inducer of hematopoietic differentiation in normal and myeloid leukemia cells, and the CAMK2N2 gene, an inhibitor of protein kinase II.