Treatment with HGF or TGF-β1 can increase the expression of the glycosyltransferase FUT8 and up-regulate the core fucosylation of N-glycans on FR FOLR1, thus enhancing folate uptake, and eventually promoting epithelial–mesenchymal transition (EMT) [71], which is the key process of cancer metastasis. This evidence concerns the gene FOLR1 and cancer.