For example, andrographolide [22], resveratrol [23], and berberine [24] can reduce inflammation of CRC by targeting the TLR4 signaling pathway, while baicalein [25], baicalin [26] , and decursin [27] can inhibit metastasis of CRC by targeting the TLR4 signaling pathway. This evidence concerns the gene TLR4 and colorectal carcinoma.