In this cohort, the primary tumor site was the parotid gland in 20 patients, the submandibular gland in 4 patients and the sublingual gland in 1 patient; to this end, a selected number of immunohistochemical markers associated with TILs (CD3, CD4, CD68 and FOXP3) and TAMs (CD68 and CD163) were examined, suggesting that the higher likelihood of LNM in the SGC may be correlated with a high density of specific TIL and TAM subpopulations [19]. The gene discussed is CD4; the disease is neoplasm.