As the BRCA1 familial variant was not sufficient to explain both pancreatic cancers, those in the patient and his sister, as well as their mother’s breast cancer, we re-initiated a CPG analysis and this showed that he carried two pathogenic variants: the known familial BRCA1 PV, and a BRCA2 PV. This evidence concerns the gene BRCA2 and familial pancreatic carcinoma.