In the literature there are studies whose results have shown that the immunohistochemical profiles of cytokeratines (CK) 7 and 20 may be useful in the differential diagnosis between primary salivary gland tumors and squamous cell carcinomas and/or tumor metastases in the salivary glands [8,29,30,31]. The gene discussed is KRT7; the disease is tumor of salivary gland.