PIK3CA and ovarian carcinoma: The onset of ovarian cancer (OC) is molecularly connected to mutagenesis of specific genes that can either regulate the expression of cell cycle/division mechanisms—generally known as proto-oncogenes, e.g., K-ras, c-myc, and c-erbB-2—as well as of genes that are involved in the cell survival pathways—downregulation of tumor suppressors, e.g., TP53, BRCA1, BRCA2, and PIK3CA [110].