S100B and early-onset autosomal dominant Alzheimer disease: S100B is used as a biomarker of brain damage [99,100], mechanical brain injury, traumatic brain injury induced by alcoholic intoxication, and long-term chemical external impacts (prolonged consumption of ethanol or other psychoactive addictive substances), as well as complex biochemical degenerative processes (associated with Parkinson and Alzheimer’s diseases) [101].