These categories include WNT (WNT1, WNT3A, WNT6, AXIN2, TNF2, MMP7), Alzheimer disease presenilin (WNT1, WNT3A, WNT6, MMP7), cadherin (WNT1, WNT3A, WNT6) and Notch (LFNG, HES1) signaling pathways. Here, CDH17 is linked to early-onset autosomal dominant Alzheimer disease.