These categories include WNT (WNT1, WNT3A, WNT6, AXIN2, TNF2, MMP7), Alzheimer disease presenilin (WNT1, WNT3A, WNT6, MMP7), cadherin (WNT1, WNT3A, WNT6) and Notch (LFNG, HES1) signaling pathways. The gene discussed is AXIN2; the disease is Alzheimer disease.