Clinical characteristics may include jaundice due to non-immune hemolysis as evidenced by a low blood hemoglobin level of 6.9 g/dL, low serum haptoglobin of <10 mg/dL, high serum activity of lactate dehydrogenase of 2148 U/L, increased serum unconjugated bilirubin of 4.5 mg/dL, and negative Coombs test [93], which classifies the hemolysis similar to the known hemolysis of genetic Wilson disease with a negative Coombs test [66], as opposed to autoimmune hemolysis with a positive Coombs test [98]. This evidence concerns the gene HP and Wilson disease.