CYP3A5 and asthma: Compared with <i>CYP3A5*3/*3</i>, the <i>CYP3A5*1/*x</i> genotype was associated with reduced weekly asthma control (OR: 0.98; 95% CI: 0.97-0.98; <i>p</i> < 0.001), increased exacerbations (OR: 6.43; 95% CI: 4.56-9.07; <i>p</i> < 0.001), and increased asthma hospitalizations (OR: 1.66; 95% CI: 1.43-1.93; <i>p</i> < 0.001); analysis of <i>3/*3</i>, <i>*1/*1</i> and <i>*1/*3</i> separately showed an allelic copy effect.